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Dementia Syndrome Revealing Acute Lymphoblastic Leukemia in Department of Neurology at Fann National Teaching Hospital in Dakar (Senegal)
Ousmane Cisse,
Marieme Soda Diop-Sène,
Soumaila Boubacar,
El Hadji Makhtar Ba,
Fatoumata Ba,
Ibrahima Mariam Diallo,
Ngor Side Diagne,
Patrice Ntenga,
Lala Bouna Seck,
Kamador Touré,
Moustapha Ndiaye,
Amadou Gallo Diop,
Mouhamadou Mansour Ndiaye
Issue:
Volume 5, Issue 2, March 2017
Pages:
16-18
Received:
19 January 2017
Accepted:
24 February 2017
Published:
27 March 2017
Abstract: Dementia is a serious disease due to its morbidity and mortality. The etiology is dominated by Alzheimer's disease. However, there are dementia syndromes related to treatable and potentially curable cause. It’s rarely reported in clinical practice in our context. We report a case of dementia associated with lymphoblastic acute leukemia complicated by lymphocytic meningitis. F. ND aged 66, widow, unschooled and unemployed was hospitalized for gait disturbance and progressive appearance of memory disorders. On physical examination, there was a dementia syndrome, bilateral pyramidal syndrome. The rest of the clinical examination associated with additional tests (thoraco-abdominal-pelvic CT scan, lumbar puncture, and myelogram) was in favor of lymphocytic meningitis and acute lymphocytic leukemia. Dementia is a disease in which the search for the cause is crucial for considering an etiological support. Blood diseases such as LAL are treatable causes. The clinic provides a guidance element of research. Also, multidisciplinary care is necessary in these kinds of patients for a better development. This scientific cooperation must be done with, hematologists, internal medicine specialists and other colleagues.
Abstract: Dementia is a serious disease due to its morbidity and mortality. The etiology is dominated by Alzheimer's disease. However, there are dementia syndromes related to treatable and potentially curable cause. It’s rarely reported in clinical practice in our context. We report a case of dementia associated with lymphoblastic acute leukemia complicated ...
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A Biermer’s Disease Revealed by a Myogeneous Syndrome About a Rare Case in Young African Black Subject and Literature Review
Fall Maouly,
Gaye Ndiaga Matar,
Cissé Ousmane,
Diop Alassane Mamadou,
Diop Marième Soda,
Ba El Hadji Makhtar,
Diagne Ngor Side,
Soumaila Boubacar,
Bass Anna Modji,
Sow Adjaratou Djeynabou,
Seck Lala Bouna,
Touré Kamadore,
Ndiaye Moustapha,
Diop Amadou Gallo,
Ndiaye Mouhamadou Mansour
Issue:
Volume 5, Issue 2, March 2017
Pages:
19-21
Received:
12 March 2017
Accepted:
24 March 2017
Published:
10 April 2017
Abstract: Biermer’s disease is an autoimmune disorder characterized by vitamin B12 deficiency. Neurological symptoms of B12 vitamin deficiency are polymorph. We report a case of a young black girl of 28 years old, senegalese student, consulted for walking ataxia and myalgia. The neurological examination found a myogenic syndrome of the four limbs. The electroneuromyogram showed diffuse myogenic involvement. The biological assessment found a macrocytic anemia at 112 fL with a vitamin B12 level collapsed at 74 pmol/L. The anti-parietal cell and anti-intrinsic factor were positive. Under supplementation with vitamin B12 the evolution is favorable after 8 months of treatment. Thus neurological deficiencies due to vitamin B12 deficiency are polymorphic. The dosage of vitamin B12 must be done before any neuropsychiatric symptoms that does not prove its worth.
Abstract: Biermer’s disease is an autoimmune disorder characterized by vitamin B12 deficiency. Neurological symptoms of B12 vitamin deficiency are polymorph. We report a case of a young black girl of 28 years old, senegalese student, consulted for walking ataxia and myalgia. The neurological examination found a myogenic syndrome of the four limbs. The electr...
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Psychoactive Substance Use Among Nigerian Students; Patterns and Sociodemographic Correlates
Chukwujekwu Chidozie Donald
Issue:
Volume 5, Issue 2, March 2017
Pages:
22-25
Received:
12 April 2017
Accepted:
18 April 2017
Published:
24 April 2017
Abstract: The increase in use and misuse of psychoactive substances is a global challenge of grave public health concern. This study aims to ascertain the patterns and socio-demographic correlates of psychoactive substances among undergraduates in a Nigerian University. Two hundred and ninety three subjects participated in the study. Questionnaires on risk factors and variation of psychoactive substances abused as well as on socio-demographic variables were administered to each participant. The prevalence of psychoactive substance use was 65.5%. the odds for use of the drugs was highest with alcohol 178(60.8%) and least for inhalational solvents 75(25.6%).There was significant association between gender and the use of: Cannabis X2 = 7.846, df=1, p<0.05, Cocaine X2 = 36.602, df=1, p<0.05,Other opioids X2 = 29.847, df=1, p<0.05, Sleeping pills X2 = 9.862, df=2, p<0.05. Nicotine X2 = 17.264, df=1, p<0.05, Inhalational solvents X2 = 6.598, df=1, p<0.05. Similarly, there was significant association between academic class and:- Cannabis X2 = 14.916, df=5, p<0.05, Heroine X2 = 12.272, df=5, p<0.05,Codeine X2 = 9.577, df=1, p<0.05, Other Opioids X2 = 15.962, df=5, p<0.05, Nicotine X2 = 15.496, df=5, p<0.05, Caffeine X2 = 13.428, df=5, p<0.05, Inhalational solvents X2 = 21.505, df=5, p<0.05. Also there was significant association between family history of use of psychoactive substances and use of Opioids X2 = 8.157, df=1, p<0.05The propensity of use of psychoactive substance has become a global emergency that requires desperate measures to curtail. This study is an effort to further emphasize this urgency.
Abstract: The increase in use and misuse of psychoactive substances is a global challenge of grave public health concern. This study aims to ascertain the patterns and socio-demographic correlates of psychoactive substances among undergraduates in a Nigerian University. Two hundred and ninety three subjects participated in the study. Questionnaires on risk f...
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Risk Factors for the Misuse of Psychoactive Substances Among University Students in the Niger Delta Region of Nigeria
Chukwujekwu Chidozie Donald
Issue:
Volume 5, Issue 2, March 2017
Pages:
26-30
Received:
12 April 2017
Accepted:
18 April 2017
Published:
24 April 2017
Abstract: The use of psychoactive substances has dire consequences for the individual and the society at large. This study aims to ascertain the risk factors for the misuse of psychoactive substances among University students in the Niger Delta region of Nigeria. Two hundred and ninety three subjects participated in the study. Questionnaires on risk factors and varieties of psychoactive substances used as well as on socio-demographic variables were administered to each participant.The most commonly used psychoactive substance was Alcohol 178(60.8%). The commonest reason for using a psychoactive substance was peer group influence 166(56.7%). Frustration was significantly associated with academic class (X2 = 17.358, df=5, p<0.05) and family history of use of the substance (X2 = 6.22, df=1, p <0.05).Academic class was also significantly associated with peer group influence (X2 = 28.914, df=5, p <0.05), parental deprivation (X2 = 20.331, df=5, p<0.05), age (X2 = 25.595, df=18, p<0.05) and influence of parents who engage in the use and abuse of substances (X2 = 22.057, df=5, p<0.05).Gender was significantly associated with influence of parents who use psychoactive substances (X2 = 9.305, df=1, p<0.05).The multiplicity of significant risk factors for psychoactive substance use underscores the need to improve the social support for students and reduce the environmental factors that make the young and impressionable minds more susceptible to drug use. The urgent need for deliberate drug- demand reduction strategies to be quickly employed in schools is imperative.
Abstract: The use of psychoactive substances has dire consequences for the individual and the society at large. This study aims to ascertain the risk factors for the misuse of psychoactive substances among University students in the Niger Delta region of Nigeria. Two hundred and ninety three subjects participated in the study. Questionnaires on risk factors ...
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