Sensitivity Factors and Human Pathology Related to Infections of Producing <i>Escherichia Coli</i> of Shiga-Toxin

Saїd Oulkheir; Khadija Ounine; Mohamed Aghrouch; Smail Chadli

doi:doi:10.11648/j.ajls.s.2017050301.19

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Sensitivity Factors and Human Pathology Related to Infections of Producing Escherichia Coli of Shiga-Toxin

Saїd Oulkheir, Khadija Ounine, Mohamed Aghrouch, Smail Chadli

Published in American Journal of Life Sciences (Volume 5, Issue 3-1)

Received: 28 November 2016 Accepted: 11 January 2017 Published: 15 April 2017

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Abstract

Escherichia coli O157: H7 is the main serotype E. coli responsible for disease in humans. STEC strains (Shiga-toxin-producing E. coli) are all strains with genes encoding Stx toxin cytotoxic for Vero cell cultures (kidney cell of African green monkey), hence the name "verotoxin"also called"Shiga toxin"because of its great similarity to a toxin produced by Shigella dysenteriae. Infections caused by EHEC (Enterohemorrhagic E. coli) are a major problem due to the extreme severity of the clinical manifestations they can generate. These translate into a banal or bloody diarrhea may develop in 5-8% of cases, mainly in young children, to a serious complication hemolytic uremic syndrome (HUS) or thrombotic thrombocytopenic purpura (TTP) in adults. The identification of susceptibility factors of clinical interest because it may allow early specific treatment of patients at risk of complications.

Published in	American Journal of Life Sciences (Volume 5, Issue 3-1) This article belongs to the Special Issue Environmental Toxicology
DOI	10.11648/j.ajls.s.2017050301.19
Page(s)	60-66
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Enterohemorrhagic E. coli, Factors of Susceptibility, Hemolytic Uremic Syndrome, Shiga-toxin-Producing E. coli, Shigatoxin

References

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Saїd Oulkheir, Khadija Ounine, Mohamed Aghrouch, Smail Chadli. (2017). Sensitivity Factors and Human Pathology Related to Infections of Producing Escherichia Coli of Shiga-Toxin. American Journal of Life Sciences, 5(3-1), 60-66. https://doi.org/10.11648/j.ajls.s.2017050301.19

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ACS Style

Saїd Oulkheir; Khadija Ounine; Mohamed Aghrouch; Smail Chadli. Sensitivity Factors and Human Pathology Related to Infections of Producing Escherichia Coli of Shiga-Toxin. Am. J. Life Sci. 2017, 5(3-1), 60-66. doi: 10.11648/j.ajls.s.2017050301.19

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AMA Style

Saїd Oulkheir, Khadija Ounine, Mohamed Aghrouch, Smail Chadli. Sensitivity Factors and Human Pathology Related to Infections of Producing Escherichia Coli of Shiga-Toxin. Am J Life Sci. 2017;5(3-1):60-66. doi: 10.11648/j.ajls.s.2017050301.19

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@article{10.11648/j.ajls.s.2017050301.19,
  author = {Saїd Oulkheir and Khadija Ounine and Mohamed Aghrouch and Smail Chadli},
  title = {Sensitivity Factors and Human Pathology Related to Infections of Producing Escherichia Coli of Shiga-Toxin},
  journal = {American Journal of Life Sciences},
  volume = {5},
  number = {3-1},
  pages = {60-66},
  doi = {10.11648/j.ajls.s.2017050301.19},
  url = {https://doi.org/10.11648/j.ajls.s.2017050301.19},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajls.s.2017050301.19},
  abstract = {Escherichia coli O157: H7 is the main serotype E. coli responsible for disease in humans. STEC strains (Shiga-toxin-producing E. coli) are all strains with genes encoding Stx toxin cytotoxic for Vero cell cultures (kidney cell of African green monkey), hence the name "verotoxin"also called"Shiga toxin"because of its great similarity to a toxin produced by Shigella dysenteriae. Infections caused by EHEC (Enterohemorrhagic E. coli) are a major problem due to the extreme severity of the clinical manifestations they can generate. These translate into a banal or bloody diarrhea may develop in 5-8% of cases, mainly in young children, to a serious complication hemolytic uremic syndrome (HUS) or thrombotic thrombocytopenic purpura (TTP) in adults. The identification of susceptibility factors of clinical interest because it may allow early specific treatment of patients at risk of complications.},
 year = {2017}
}

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TY  - JOUR
T1  - Sensitivity Factors and Human Pathology Related to Infections of Producing Escherichia Coli of Shiga-Toxin
AU  - Saїd Oulkheir
AU  - Khadija Ounine
AU  - Mohamed Aghrouch
AU  - Smail Chadli
Y1  - 2017/04/15
PY  - 2017
N1  - https://doi.org/10.11648/j.ajls.s.2017050301.19
DO  - 10.11648/j.ajls.s.2017050301.19
T2  - American Journal of Life Sciences
JF  - American Journal of Life Sciences
JO  - American Journal of Life Sciences
SP  - 60
EP  - 66
PB  - Science Publishing Group
SN  - 2328-5737
UR  - https://doi.org/10.11648/j.ajls.s.2017050301.19
AB  - Escherichia coli O157: H7 is the main serotype E. coli responsible for disease in humans. STEC strains (Shiga-toxin-producing E. coli) are all strains with genes encoding Stx toxin cytotoxic for Vero cell cultures (kidney cell of African green monkey), hence the name "verotoxin"also called"Shiga toxin"because of its great similarity to a toxin produced by Shigella dysenteriae. Infections caused by EHEC (Enterohemorrhagic E. coli) are a major problem due to the extreme severity of the clinical manifestations they can generate. These translate into a banal or bloody diarrhea may develop in 5-8% of cases, mainly in young children, to a serious complication hemolytic uremic syndrome (HUS) or thrombotic thrombocytopenic purpura (TTP) in adults. The identification of susceptibility factors of clinical interest because it may allow early specific treatment of patients at risk of complications.
VL  - 5
IS  - 3-1
ER  -

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Author Information

Saїd Oulkheir
Khadija Ounine

Laboratory of Applied Microbiology Department of Biology, Faculty of Sciences, Ibn Tofail University, Kenitra, Morocco
Mohamed Aghrouch

Laboratory of Medical Analysis, Hospital Hassan II, Agadir, Morocco
Smail Chadli

High Institute of Nursing Professions and Health Techniques, ISPITS, Agadir, Morocco

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Plain Text BibTeX RIS

APA Style

Saїd Oulkheir, Khadija Ounine, Mohamed Aghrouch, Smail Chadli. (2017). Sensitivity Factors and Human Pathology Related to Infections of Producing Escherichia Coli of Shiga-Toxin. American Journal of Life Sciences, 5(3-1), 60-66. https://doi.org/10.11648/j.ajls.s.2017050301.19

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ACS Style

Saїd Oulkheir; Khadija Ounine; Mohamed Aghrouch; Smail Chadli. Sensitivity Factors and Human Pathology Related to Infections of Producing Escherichia Coli of Shiga-Toxin. Am. J. Life Sci. 2017, 5(3-1), 60-66. doi: 10.11648/j.ajls.s.2017050301.19

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AMA Style

Saїd Oulkheir, Khadija Ounine, Mohamed Aghrouch, Smail Chadli. Sensitivity Factors and Human Pathology Related to Infections of Producing Escherichia Coli of Shiga-Toxin. Am J Life Sci. 2017;5(3-1):60-66. doi: 10.11648/j.ajls.s.2017050301.19

Copy | Download

@article{10.11648/j.ajls.s.2017050301.19,
  author = {Saїd Oulkheir and Khadija Ounine and Mohamed Aghrouch and Smail Chadli},
  title = {Sensitivity Factors and Human Pathology Related to Infections of Producing Escherichia Coli of Shiga-Toxin},
  journal = {American Journal of Life Sciences},
  volume = {5},
  number = {3-1},
  pages = {60-66},
  doi = {10.11648/j.ajls.s.2017050301.19},
  url = {https://doi.org/10.11648/j.ajls.s.2017050301.19},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajls.s.2017050301.19},
  abstract = {Escherichia coli O157: H7 is the main serotype E. coli responsible for disease in humans. STEC strains (Shiga-toxin-producing E. coli) are all strains with genes encoding Stx toxin cytotoxic for Vero cell cultures (kidney cell of African green monkey), hence the name "verotoxin"also called"Shiga toxin"because of its great similarity to a toxin produced by Shigella dysenteriae. Infections caused by EHEC (Enterohemorrhagic E. coli) are a major problem due to the extreme severity of the clinical manifestations they can generate. These translate into a banal or bloody diarrhea may develop in 5-8% of cases, mainly in young children, to a serious complication hemolytic uremic syndrome (HUS) or thrombotic thrombocytopenic purpura (TTP) in adults. The identification of susceptibility factors of clinical interest because it may allow early specific treatment of patients at risk of complications.},
 year = {2017}
}

Copy | Download

TY  - JOUR
T1  - Sensitivity Factors and Human Pathology Related to Infections of Producing Escherichia Coli of Shiga-Toxin
AU  - Saїd Oulkheir
AU  - Khadija Ounine
AU  - Mohamed Aghrouch
AU  - Smail Chadli
Y1  - 2017/04/15
PY  - 2017
N1  - https://doi.org/10.11648/j.ajls.s.2017050301.19
DO  - 10.11648/j.ajls.s.2017050301.19
T2  - American Journal of Life Sciences
JF  - American Journal of Life Sciences
JO  - American Journal of Life Sciences
SP  - 60
EP  - 66
PB  - Science Publishing Group
SN  - 2328-5737
UR  - https://doi.org/10.11648/j.ajls.s.2017050301.19
AB  - Escherichia coli O157: H7 is the main serotype E. coli responsible for disease in humans. STEC strains (Shiga-toxin-producing E. coli) are all strains with genes encoding Stx toxin cytotoxic for Vero cell cultures (kidney cell of African green monkey), hence the name "verotoxin"also called"Shiga toxin"because of its great similarity to a toxin produced by Shigella dysenteriae. Infections caused by EHEC (Enterohemorrhagic E. coli) are a major problem due to the extreme severity of the clinical manifestations they can generate. These translate into a banal or bloody diarrhea may develop in 5-8% of cases, mainly in young children, to a serious complication hemolytic uremic syndrome (HUS) or thrombotic thrombocytopenic purpura (TTP) in adults. The identification of susceptibility factors of clinical interest because it may allow early specific treatment of patients at risk of complications.
VL  - 5
IS  - 3-1
ER  -

Copy | Download