Phytochemical Screening and Biological Activity Studies of the Extract from the Bark of <i>Ricinodendron heudoletti</i>, Euphorbiaceae

Oyono Victor; Fokunang Charles; Tembe-Fokunang Estella; Tsague Marthe; Messi Angélique; Assam Jean; Ngameni Bethelemy; Kechia Frederick; Armel Herve Nwabo Kamdje; Penlap Veronique; Ngadjui Bonaventure

doi:doi:10.11648/j.jdmp.20160206.14

Phytochemical Screening and Biological Activity Studies of the Extract from the Bark of Ricinodendron heudoletti, Euphorbiaceae

Oyono Victor, Fokunang Charles, Tembe-Fokunang Estella, Tsague Marthe, Messi Angélique, Assam Jean, Ngameni Bethelemy, Kechia Frederick, Armel Herve Nwabo Kamdje, Penlap Veronique, Ngadjui Bonaventure

Published in Journal of Diseases and Medicinal Plants (Volume 2, Issue 6)

Received: 6 July 2016 Accepted: 12 July 2016 Published: 10 January 2017

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Abstract

The fractions and pure compounds isolated from the bark of R. heudoletti were tested for their antibacterial properties on negative and positive gram bacteria using the disc diffusion method. Phytochemical analysis of the fractions and pure compound isolated was also conducted. The inhibitions parameters of the fractions and pure compound were determined using macro dilution method. The results showed that fraction and isoflavonoid exhibited a significant antibacterial effect against twelve strains isolated from patients. These micro-organisms were Gram-negative (Escherichia coli, Salmonella typhi, Shigella flexneri, Pseudomonas aeroginosa, Enterobacter cloacae, Klebsiella pneumoniae, Klebsiella oxytoca, Morganella morganii, Citrobacter freundi, and Proteus vulgaris) and positive gram (Staphylococcus aureus, and Streptococcus feacalis). The ratio of minimal bactericidal concentration (MBC) over the minimal inhibitory concentration (MIC) indicated a promising bactericidal effect of fractions and pure compounds isolated. These results support the current common use of the bark of Ricinodendron heudoletti and flavonoids in the treatment of some infectious diseases.

Published in	Journal of Diseases and Medicinal Plants (Volume 2, Issue 6)
DOI	10.11648/j.jdmp.20160206.14
Page(s)	83-89
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Biochemistry Properties, Flavonoids, Infectious Diseases, Ricinodendron heudoletti

References

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[5]	Oyono VA 1, Fokunang CN, 1, Assam JP, Voundi S, Tsafack P, Tetwe EM, Ngadjui BT. 2014. Acute toxicity studies, antioxidant and in vitro antibacterial activities of extract from the barks of Ricinodendron heudoletti (Euphorbiaceae). Journal of Pharmacognosy and Phytotherapy Vol. 6 (4), pp. 47-53, DOI: 10.5897/JPP2014.0312, http://www.academicjournals.org/JPP.
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APA Style

Oyono Victor, Fokunang Charles, Tembe-Fokunang Estella, Tsague Marthe, Messi Angélique, et al. (2017). Phytochemical Screening and Biological Activity Studies of the Extract from the Bark of Ricinodendron heudoletti, Euphorbiaceae. Journal of Diseases and Medicinal Plants, 2(6), 83-89. https://doi.org/10.11648/j.jdmp.20160206.14

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ACS Style

Oyono Victor; Fokunang Charles; Tembe-Fokunang Estella; Tsague Marthe; Messi Angélique, et al. Phytochemical Screening and Biological Activity Studies of the Extract from the Bark of Ricinodendron heudoletti, Euphorbiaceae. J. Dis. Med. Plants 2017, 2(6), 83-89. doi: 10.11648/j.jdmp.20160206.14

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AMA Style

Oyono Victor, Fokunang Charles, Tembe-Fokunang Estella, Tsague Marthe, Messi Angélique, et al. Phytochemical Screening and Biological Activity Studies of the Extract from the Bark of Ricinodendron heudoletti, Euphorbiaceae. J Dis Med Plants. 2017;2(6):83-89. doi: 10.11648/j.jdmp.20160206.14

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@article{10.11648/j.jdmp.20160206.14,
  author = {Oyono Victor and Fokunang Charles and Tembe-Fokunang Estella and Tsague Marthe and Messi Angélique and Assam Jean and Ngameni Bethelemy and Kechia Frederick and Armel Herve Nwabo Kamdje and Penlap Veronique and Ngadjui Bonaventure},
  title = {Phytochemical Screening and Biological Activity Studies of the Extract from the Bark of Ricinodendron heudoletti, Euphorbiaceae},
  journal = {Journal of Diseases and Medicinal Plants},
  volume = {2},
  number = {6},
  pages = {83-89},
  doi = {10.11648/j.jdmp.20160206.14},
  url = {https://doi.org/10.11648/j.jdmp.20160206.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jdmp.20160206.14},
  abstract = {The fractions and pure compounds isolated from the bark of R. heudoletti were tested for their antibacterial properties on negative and positive gram bacteria using the disc diffusion method. Phytochemical analysis of the fractions and pure compound isolated was also conducted. The inhibitions parameters of the fractions and pure compound were determined using macro dilution method. The results showed that fraction and isoflavonoid exhibited a significant antibacterial effect against twelve strains isolated from patients. These micro-organisms were Gram-negative (Escherichia coli, Salmonella typhi, Shigella flexneri, Pseudomonas aeroginosa, Enterobacter cloacae, Klebsiella pneumoniae, Klebsiella oxytoca, Morganella morganii, Citrobacter freundi, and Proteus vulgaris) and positive gram (Staphylococcus aureus, and Streptococcus feacalis). The ratio of minimal bactericidal concentration (MBC) over the minimal inhibitory concentration (MIC) indicated a promising bactericidal effect of fractions and pure compounds isolated. These results support the current common use of the bark of Ricinodendron heudoletti and flavonoids in the treatment of some infectious diseases.},
 year = {2017}
}

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TY  - JOUR
T1  - Phytochemical Screening and Biological Activity Studies of the Extract from the Bark of Ricinodendron heudoletti, Euphorbiaceae
AU  - Oyono Victor
AU  - Fokunang Charles
AU  - Tembe-Fokunang Estella
AU  - Tsague Marthe
AU  - Messi Angélique
AU  - Assam Jean
AU  - Ngameni Bethelemy
AU  - Kechia Frederick
AU  - Armel Herve Nwabo Kamdje
AU  - Penlap Veronique
AU  - Ngadjui Bonaventure
Y1  - 2017/01/10
PY  - 2017
N1  - https://doi.org/10.11648/j.jdmp.20160206.14
DO  - 10.11648/j.jdmp.20160206.14
T2  - Journal of Diseases and Medicinal Plants
JF  - Journal of Diseases and Medicinal Plants
JO  - Journal of Diseases and Medicinal Plants
SP  - 83
EP  - 89
PB  - Science Publishing Group
SN  - 2469-8210
UR  - https://doi.org/10.11648/j.jdmp.20160206.14
AB  - The fractions and pure compounds isolated from the bark of R. heudoletti were tested for their antibacterial properties on negative and positive gram bacteria using the disc diffusion method. Phytochemical analysis of the fractions and pure compound isolated was also conducted. The inhibitions parameters of the fractions and pure compound were determined using macro dilution method. The results showed that fraction and isoflavonoid exhibited a significant antibacterial effect against twelve strains isolated from patients. These micro-organisms were Gram-negative (Escherichia coli, Salmonella typhi, Shigella flexneri, Pseudomonas aeroginosa, Enterobacter cloacae, Klebsiella pneumoniae, Klebsiella oxytoca, Morganella morganii, Citrobacter freundi, and Proteus vulgaris) and positive gram (Staphylococcus aureus, and Streptococcus feacalis). The ratio of minimal bactericidal concentration (MBC) over the minimal inhibitory concentration (MIC) indicated a promising bactericidal effect of fractions and pure compounds isolated. These results support the current common use of the bark of Ricinodendron heudoletti and flavonoids in the treatment of some infectious diseases.
VL  - 2
IS  - 6
ER  -

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Author Information

Oyono Victor

Department of Pharmaceutical Sciences and Traditional Pharmacopeia, Faculty of Medicine and Biomedical Sciences, University of Yaounde 1, Yaounde, Cameroon
Fokunang Charles

Department of Pharmaceutical Sciences and Traditional Pharmacopeia, Faculty of Medicine and Biomedical Sciences, University of Yaounde 1, Yaounde, Cameroon
Tembe-Fokunang Estella

Department of Pharmaceutical Sciences and Traditional Pharmacopeia, Faculty of Medicine and Biomedical Sciences, University of Yaounde 1, Yaounde, Cameroon
Tsague Marthe

Department of Pharmaceutical Sciences and Traditional Pharmacopeia, Faculty of Medicine and Biomedical Sciences, University of Yaounde 1, Yaounde, Cameroon
Messi Angélique

Department of Biochemistry, Faculty of Sciences, University of Yaounde 1, Yaounde, Yaounde, Cameroon
Assam Jean

Department of Biochemistry, Faculty of Sciences, University of Douala, Douala, Cameroon
Ngameni Bethelemy

Department of Pharmaceutical Sciences and Traditional Pharmacopeia, Faculty of Medicine and Biomedical Sciences, University of Yaounde 1, Yaounde, Cameroon
Kechia Frederick

Department of Pharmaceutical Sciences and Traditional Pharmacopeia, Faculty of Medicine and Biomedical Sciences, University of Yaounde 1, Yaounde, Cameroon
Armel Herve Nwabo Kamdje

Department of Biological Sciences, University of Ngaoundere, Ngaoundere, Cameroon
Penlap Veronique

Department of Biochemistry, Faculty of Sciences, University of Yaounde 1, Yaounde, Yaounde, Cameroon
Ngadjui Bonaventure

Department of Pharmaceutical Sciences and Traditional Pharmacopeia, Faculty of Medicine and Biomedical Sciences, University of Yaounde 1, Yaounde, Cameroon

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APA Style

Oyono Victor, Fokunang Charles, Tembe-Fokunang Estella, Tsague Marthe, Messi Angélique, et al. (2017). Phytochemical Screening and Biological Activity Studies of the Extract from the Bark of Ricinodendron heudoletti, Euphorbiaceae. Journal of Diseases and Medicinal Plants, 2(6), 83-89. https://doi.org/10.11648/j.jdmp.20160206.14

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ACS Style

Oyono Victor; Fokunang Charles; Tembe-Fokunang Estella; Tsague Marthe; Messi Angélique, et al. Phytochemical Screening and Biological Activity Studies of the Extract from the Bark of Ricinodendron heudoletti, Euphorbiaceae. J. Dis. Med. Plants 2017, 2(6), 83-89. doi: 10.11648/j.jdmp.20160206.14

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AMA Style

Oyono Victor, Fokunang Charles, Tembe-Fokunang Estella, Tsague Marthe, Messi Angélique, et al. Phytochemical Screening and Biological Activity Studies of the Extract from the Bark of Ricinodendron heudoletti, Euphorbiaceae. J Dis Med Plants. 2017;2(6):83-89. doi: 10.11648/j.jdmp.20160206.14

Copy | Download

@article{10.11648/j.jdmp.20160206.14,
  author = {Oyono Victor and Fokunang Charles and Tembe-Fokunang Estella and Tsague Marthe and Messi Angélique and Assam Jean and Ngameni Bethelemy and Kechia Frederick and Armel Herve Nwabo Kamdje and Penlap Veronique and Ngadjui Bonaventure},
  title = {Phytochemical Screening and Biological Activity Studies of the Extract from the Bark of Ricinodendron heudoletti, Euphorbiaceae},
  journal = {Journal of Diseases and Medicinal Plants},
  volume = {2},
  number = {6},
  pages = {83-89},
  doi = {10.11648/j.jdmp.20160206.14},
  url = {https://doi.org/10.11648/j.jdmp.20160206.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jdmp.20160206.14},
  abstract = {The fractions and pure compounds isolated from the bark of R. heudoletti were tested for their antibacterial properties on negative and positive gram bacteria using the disc diffusion method. Phytochemical analysis of the fractions and pure compound isolated was also conducted. The inhibitions parameters of the fractions and pure compound were determined using macro dilution method. The results showed that fraction and isoflavonoid exhibited a significant antibacterial effect against twelve strains isolated from patients. These micro-organisms were Gram-negative (Escherichia coli, Salmonella typhi, Shigella flexneri, Pseudomonas aeroginosa, Enterobacter cloacae, Klebsiella pneumoniae, Klebsiella oxytoca, Morganella morganii, Citrobacter freundi, and Proteus vulgaris) and positive gram (Staphylococcus aureus, and Streptococcus feacalis). The ratio of minimal bactericidal concentration (MBC) over the minimal inhibitory concentration (MIC) indicated a promising bactericidal effect of fractions and pure compounds isolated. These results support the current common use of the bark of Ricinodendron heudoletti and flavonoids in the treatment of some infectious diseases.},
 year = {2017}
}

Copy | Download

TY  - JOUR
T1  - Phytochemical Screening and Biological Activity Studies of the Extract from the Bark of Ricinodendron heudoletti, Euphorbiaceae
AU  - Oyono Victor
AU  - Fokunang Charles
AU  - Tembe-Fokunang Estella
AU  - Tsague Marthe
AU  - Messi Angélique
AU  - Assam Jean
AU  - Ngameni Bethelemy
AU  - Kechia Frederick
AU  - Armel Herve Nwabo Kamdje
AU  - Penlap Veronique
AU  - Ngadjui Bonaventure
Y1  - 2017/01/10
PY  - 2017
N1  - https://doi.org/10.11648/j.jdmp.20160206.14
DO  - 10.11648/j.jdmp.20160206.14
T2  - Journal of Diseases and Medicinal Plants
JF  - Journal of Diseases and Medicinal Plants
JO  - Journal of Diseases and Medicinal Plants
SP  - 83
EP  - 89
PB  - Science Publishing Group
SN  - 2469-8210
UR  - https://doi.org/10.11648/j.jdmp.20160206.14
AB  - The fractions and pure compounds isolated from the bark of R. heudoletti were tested for their antibacterial properties on negative and positive gram bacteria using the disc diffusion method. Phytochemical analysis of the fractions and pure compound isolated was also conducted. The inhibitions parameters of the fractions and pure compound were determined using macro dilution method. The results showed that fraction and isoflavonoid exhibited a significant antibacterial effect against twelve strains isolated from patients. These micro-organisms were Gram-negative (Escherichia coli, Salmonella typhi, Shigella flexneri, Pseudomonas aeroginosa, Enterobacter cloacae, Klebsiella pneumoniae, Klebsiella oxytoca, Morganella morganii, Citrobacter freundi, and Proteus vulgaris) and positive gram (Staphylococcus aureus, and Streptococcus feacalis). The ratio of minimal bactericidal concentration (MBC) over the minimal inhibitory concentration (MIC) indicated a promising bactericidal effect of fractions and pure compounds isolated. These results support the current common use of the bark of Ricinodendron heudoletti and flavonoids in the treatment of some infectious diseases.
VL  - 2
IS  - 6
ER  -

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