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Psychiatric Psychobiological Treatment Versus Exclusive Psychological Treatment in Depressive Disorders

Received: 14 January 2023    Accepted: 3 February 2023    Published: 16 February 2023
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Abstract

Introduction: Scientific information on the antidepressant effectiveness of the varied usual therapeutic interventions is considerable but of poor quality. Objective: To analyse the scientifically well qualified international contributions on the effectiveness of habitual psychobiological psychiatric interventions in depressive disorders. Method: N= 6 structured bibliographic systems have been reviewed in a non-systematic, narrative and synthetic way and N= 75 significant contributions have been selected. Results and discussion: Patients with severe depression are more likely to receive any type of medical attention, but less likely to receive adequate attention. The use of both drugs and psychotherapy is the habitual mixed combined intervention during any ordinary psychiatric treatment. We will call it psychobiological or psychopharmacological intervention. The exclusive psychological intervention without using any medically prescribed drugs, is likely to be less cost/effective. The matter is not only to prioritise but also to adequately combine psychiatric interventions and added psychological interventions when convenient. The intervention on the neurophysiological pathways related with glutamate, the GABAergic, opioidergic, and inflammatory systems as well as on connectome and microbiome are being promoted for future drug antidepressant therapy with encouraging results. Conclusion: The mixed psychiatric option using drugs and psychotherapy, either regulated or not, by the intervening psychiatrist himself or herself is probably the main therapeutic choice for the correctly diagnosed depressive disorders. The psychotherapeutics intervention excluding the psychobiological psychiatric intervention in correctly diagnosed depressions will be insufficient in general. The professional psychological intervention may obviously complement the mixed psychiatric intervention, but can not replace it.

Published in American Journal of Psychiatry and Neuroscience (Volume 11, Issue 1)
DOI 10.11648/j.ajpn.20231101.12
Page(s) 13-21
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2023. Published by Science Publishing Group

Keywords

Depressive Disorder, Depression, Mini-Review, Psychobiology, Psychopharmacology, Psychotherapy, Treatment of Resistant Depression

References
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    José Manuel Bertolín-Guillén. (2023). Psychiatric Psychobiological Treatment Versus Exclusive Psychological Treatment in Depressive Disorders. American Journal of Psychiatry and Neuroscience, 11(1), 13-21. https://doi.org/10.11648/j.ajpn.20231101.12

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    José Manuel Bertolín-Guillén. Psychiatric Psychobiological Treatment Versus Exclusive Psychological Treatment in Depressive Disorders. Am. J. Psychiatry Neurosci. 2023, 11(1), 13-21. doi: 10.11648/j.ajpn.20231101.12

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    José Manuel Bertolín-Guillén. Psychiatric Psychobiological Treatment Versus Exclusive Psychological Treatment in Depressive Disorders. Am J Psychiatry Neurosci. 2023;11(1):13-21. doi: 10.11648/j.ajpn.20231101.12

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  • @article{10.11648/j.ajpn.20231101.12,
      author = {José Manuel Bertolín-Guillén},
      title = {Psychiatric Psychobiological Treatment Versus Exclusive Psychological Treatment in Depressive Disorders},
      journal = {American Journal of Psychiatry and Neuroscience},
      volume = {11},
      number = {1},
      pages = {13-21},
      doi = {10.11648/j.ajpn.20231101.12},
      url = {https://doi.org/10.11648/j.ajpn.20231101.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajpn.20231101.12},
      abstract = {Introduction: Scientific information on the antidepressant effectiveness of the varied usual therapeutic interventions is considerable but of poor quality. Objective: To analyse the scientifically well qualified international contributions on the effectiveness of habitual psychobiological psychiatric interventions in depressive disorders. Method: N= 6 structured bibliographic systems have been reviewed in a non-systematic, narrative and synthetic way and N= 75 significant contributions have been selected. Results and discussion: Patients with severe depression are more likely to receive any type of medical attention, but less likely to receive adequate attention. The use of both drugs and psychotherapy is the habitual mixed combined intervention during any ordinary psychiatric treatment. We will call it psychobiological or psychopharmacological intervention. The exclusive psychological intervention without using any medically prescribed drugs, is likely to be less cost/effective. The matter is not only to prioritise but also to adequately combine psychiatric interventions and added psychological interventions when convenient. The intervention on the neurophysiological pathways related with glutamate, the GABAergic, opioidergic, and inflammatory systems as well as on connectome and microbiome are being promoted for future drug antidepressant therapy with encouraging results. Conclusion: The mixed psychiatric option using drugs and psychotherapy, either regulated or not, by the intervening psychiatrist himself or herself is probably the main therapeutic choice for the correctly diagnosed depressive disorders. The psychotherapeutics intervention excluding the psychobiological psychiatric intervention in correctly diagnosed depressions will be insufficient in general. The professional psychological intervention may obviously complement the mixed psychiatric intervention, but can not replace it.},
     year = {2023}
    }
    

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    T2  - American Journal of Psychiatry and Neuroscience
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    SN  - 2330-426X
    UR  - https://doi.org/10.11648/j.ajpn.20231101.12
    AB  - Introduction: Scientific information on the antidepressant effectiveness of the varied usual therapeutic interventions is considerable but of poor quality. Objective: To analyse the scientifically well qualified international contributions on the effectiveness of habitual psychobiological psychiatric interventions in depressive disorders. Method: N= 6 structured bibliographic systems have been reviewed in a non-systematic, narrative and synthetic way and N= 75 significant contributions have been selected. Results and discussion: Patients with severe depression are more likely to receive any type of medical attention, but less likely to receive adequate attention. The use of both drugs and psychotherapy is the habitual mixed combined intervention during any ordinary psychiatric treatment. We will call it psychobiological or psychopharmacological intervention. The exclusive psychological intervention without using any medically prescribed drugs, is likely to be less cost/effective. The matter is not only to prioritise but also to adequately combine psychiatric interventions and added psychological interventions when convenient. The intervention on the neurophysiological pathways related with glutamate, the GABAergic, opioidergic, and inflammatory systems as well as on connectome and microbiome are being promoted for future drug antidepressant therapy with encouraging results. Conclusion: The mixed psychiatric option using drugs and psychotherapy, either regulated or not, by the intervening psychiatrist himself or herself is probably the main therapeutic choice for the correctly diagnosed depressive disorders. The psychotherapeutics intervention excluding the psychobiological psychiatric intervention in correctly diagnosed depressions will be insufficient in general. The professional psychological intervention may obviously complement the mixed psychiatric intervention, but can not replace it.
    VL  - 11
    IS  - 1
    ER  - 

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  • Mental Health and Psychiatry Service (Retired) in a Department of Health, Ministry for Universal Healthcare and Public Health, Government of Valencia, Valencia, Spain

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