Bone is endocrine metabolic organ which maintains its integrity through the process of bone remodeling controlled by several local and systemic factors. Any perturbation in the bone remodeling leads to development of osteoporosis which is mostly age related but can be premature as well. Several therapies have come up to treat osteoporosis including bisphosphonates but due to side effects natural compounds are looked like resveratrol which has estrogenic property depending upon the type of tissue it is acting upon. Resveratrol has stimulatory effect on bone cells by modulating the process of differentiation through change in the expression levels of osteoblastic genes through estrogen receptors.
| Published in | American Journal of Life Sciences (Volume 6, Issue 1) |
| DOI | 10.11648/j.ajls.20180601.14 |
| Page(s) | 22-28 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2018. Published by Science Publishing Group |
Bone Remodeling, Osteoporosis, Phytoestrogen, Resveratrol
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APA Style
Poonam Kanta, Dheeraj Dumir, Alka Khera. (2018). Regulation of Osteoblastic Differentiation: A Concept Note. American Journal of Life Sciences, 6(1), 22-28. https://doi.org/10.11648/j.ajls.20180601.14
ACS Style
Poonam Kanta; Dheeraj Dumir; Alka Khera. Regulation of Osteoblastic Differentiation: A Concept Note. Am. J. Life Sci. 2018, 6(1), 22-28. doi: 10.11648/j.ajls.20180601.14
AMA Style
Poonam Kanta, Dheeraj Dumir, Alka Khera. Regulation of Osteoblastic Differentiation: A Concept Note. Am J Life Sci. 2018;6(1):22-28. doi: 10.11648/j.ajls.20180601.14
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Download@article{10.11648/j.ajls.20180601.14,
author = {Poonam Kanta and Dheeraj Dumir and Alka Khera},
title = {Regulation of Osteoblastic Differentiation: A Concept Note},
journal = {American Journal of Life Sciences},
volume = {6},
number = {1},
pages = {22-28},
doi = {10.11648/j.ajls.20180601.14},
url = {https://doi.org/10.11648/j.ajls.20180601.14},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajls.20180601.14},
abstract = {Bone is endocrine metabolic organ which maintains its integrity through the process of bone remodeling controlled by several local and systemic factors. Any perturbation in the bone remodeling leads to development of osteoporosis which is mostly age related but can be premature as well. Several therapies have come up to treat osteoporosis including bisphosphonates but due to side effects natural compounds are looked like resveratrol which has estrogenic property depending upon the type of tissue it is acting upon. Resveratrol has stimulatory effect on bone cells by modulating the process of differentiation through change in the expression levels of osteoblastic genes through estrogen receptors.},
year = {2018}
}
TY - JOUR T1 - Regulation of Osteoblastic Differentiation: A Concept Note AU - Poonam Kanta AU - Dheeraj Dumir AU - Alka Khera Y1 - 2018/06/26 PY - 2018 N1 - https://doi.org/10.11648/j.ajls.20180601.14 DO - 10.11648/j.ajls.20180601.14 T2 - American Journal of Life Sciences JF - American Journal of Life Sciences JO - American Journal of Life Sciences SP - 22 EP - 28 PB - Science Publishing Group SN - 2328-5737 UR - https://doi.org/10.11648/j.ajls.20180601.14 AB - Bone is endocrine metabolic organ which maintains its integrity through the process of bone remodeling controlled by several local and systemic factors. Any perturbation in the bone remodeling leads to development of osteoporosis which is mostly age related but can be premature as well. Several therapies have come up to treat osteoporosis including bisphosphonates but due to side effects natural compounds are looked like resveratrol which has estrogenic property depending upon the type of tissue it is acting upon. Resveratrol has stimulatory effect on bone cells by modulating the process of differentiation through change in the expression levels of osteoblastic genes through estrogen receptors. VL - 6 IS - 1 ER -
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